AMA’s Infrared Protection Offerings at the In Vivo and In Vitro Level
Infrared radiation (IR) was long considered harmless; however, it is now identified as a major contributor to photo-damage and photo-aging.1 To meet the growing demand for IR protection, AMA developed a new method for evaluating the Infrared Protection Factor (IRPF™) of topical skin care/sun care products. It represents a fully validated, unbiased independent test.*
The In-Vitro method is fully validated against In-Vivo results, all patterned after current ISO and FDA regulatory standards. A final In-Vitro and/or In-Vivo report is issued at the conclusion of the study, signed and dated by all relevant staff scientists, defining the product’s ability to reduce the visible effects of IR.
State-of-the-art spectroradiometric equipment used in testing the material is fully customized and calibrated to National Institute of Standards and Technology (NIST) traceable standards. All In-Vitro results can be further verified visually and instrumentally in two test subjects and against the In-Vivo data for an additional fee. The formal test protocol is available upon request for a fee, fully applicable to a study being placed with AMA.
More About Our Tests
In-Vitro testing designates infrared protection capabilities via an in-house generated factor. This factor is based on in-vivo SPF values and interpolates percentage protection as a function of the transmission values of a film obtained during spectroradiometric measurements. We perform spectroradiometric measurements over the range of 700-1440nm (IRA), as well as the full spectrum up to -2500nm (IR). Sample reports are available.
In-Vivo testing addresses the immediate, visible biological response of skin exposed to infrared radiation (before any permanent damage may occur).1 The visible response (erythema) is acquired and evaluated using our Matched Scientific Photo Analysis (PhotoGrammetrix®).
*Notice: This test method has not been reviewed nor is in any way authorized by ISO (International Standards Organization), the FDA (U. S. Food and Drug Administration) or any other global regulatory agency. The test report provides no warranties or guarantees for labeling and/or claim substantiation either implied or expressed.